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Drug production

Liquid and solid production

Pharmaceutical manufacturing is a highly controlled and regulated environment. The production is made in an isolator, where decontamination is mandatory and monitored. Almost every process can be automated to gain in flexibility and sterility.

Get inspired by our solutions from API production to end of line packaging:

The Active Pharmaceutical Ingredient industry (API) are manufactured from raw materials through both chemical and physical means. Depending on the complexity of the molecule required, synthesis of APIs might need multi-step complex chemistry utilizing a range of processing technologies. Regardless of where the active pharmaceutical ingredient is made, companies must adhere to strict safety and quality standards set by the country where it will be used.

Active Pharmaceutical Ingredient production 3D line
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Small Batch API production within Isolator with TX2-160 Stericlean opening powder bulk and feeding filling line

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Example of Mobility upgrade where TX2-160 unload empty bulk from Isolator and use AGV for transportation to logistic area

Main applications

  • Bulk powder handling
  • Transportation of API Vessel
  • API logistics
❝ Robots become the ideal partner to handle sensitive substances, allowing people to devote themselves to tasks where their knowledge is irreplaceable. ❞

RUDOLF MICHAEL WEISS | GLOBAL HEAD OF PHARMA ROBOTICS

To respond efficiently to market expectations, production must be easily scalable, the robot’s flexibility being a key factor to enable this.

Whether in a small isolator with a single robot capable of handling several independent or linked operations, or in a complete production line equipped with multiple robots, they allow management of different RTU containers in order to change production easily, should the need arise.

Primary packaging 3D line for drug production
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Filling and closing syringes with a TX60 Cleanroom
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Vials filling by TX2-40 Stericlean within isolator

A Stäubli TX2-90 six-axis robot is used for the fully automated filling of HA gel in an aseptic environment.
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Transfer of 5 vials with antisloshing movement by TX2-60 Stericlean

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Stopper placement & Capping of the filled vials by TX2-40 Stericlean

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TX2-60 Stericlean places filled vials into trays

Main applications

  • Filling
  • De-nesting / Re-nesting
  • Bag and TUB opening
  • Inspection
  • Weighing
  • Transferring
  • Lyophilization
  • Capping
  • Stopper handling
  • Solid gravimetric filling
  • Compacting
❝ With impressive levels of flexibility, robotbased automation solutions are the first choice for small batch production runs. ❞

RUDOLF MICHAEL WEISS | GLOBAL HEAD OF PHARMA ROBOTICS

Success stories

Once individually packed, the journey to shipment starts. The requirements within the secondary packaging area is less restrictive than within an isolator, however the cleanability of equipment still has an essential role. Throughout the task, traceability is mandatory, with robotics offering huge flexibility for inspection at each stage of the process.

With quality assurance having the most stringent requirements, we foresee more and more demand on inspection units. On the secondary packaging area, collaborative aspects of the robots can be considered to ensure safety of the workers while sustaining high levels of productivity.

Secondary packaging 3D line for drug production
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TX2-60 places a filled syringe into a blister

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SCARA robot for secondary packaging

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Palletizing with TX2-160 and Automated forklift move the pallet to Logistic area

Main applications

  • Container Handling
  • Inspection
  • Device and component assembly
  • Blistering
  • Labelling
  • Cartoning
  • Transferring
  • Palettizing
  • Tracking
❝ From the first molecule to the shipment, robots play an essential role in the pharma manufacturing chain. ❞

RUDOLF MICHAEL WEISS | GLOBAL HEAD OF PHARMA ROBOTICS

Success stories

Our dedicated robot lines